High Evidence Drugs
Priority candidates for clinical evaluation
Evidence Standards
| Level | Definition | Clinical Significance |
|---|---|---|
| L1 | Multiple Phase 3 RCTs / Systematic Reviews | Strong support, consider clinical use |
| L2 | Single RCT or multiple Phase 2 trials | Moderate support, design validation trials |
Drug List
L1 Level (94 drugs)
| Drug Name | Predictions | Link |
|---|---|---|
| Acetylcysteine | 5 | View Report |
| Acyclovir | 5 | View Report |
| Adalimumab | 5 | View Report |
| Albendazole | 5 | View Report |
| Amphotericin B | 5 | View Report |
| Aripiprazole | 5 | View Report |
| Atenolol | 5 | View Report |
| Azacitidine | 5 | View Report |
| Beclomethasone Dipropionate | 5 | View Report |
| Betamethasone | 5 | View Report |
| Bevacizumab | 5 | View Report |
| Bortezomib | 5 | View Report |
| Budesonide | 5 | View Report |
| Caffeine | 5 | View Report |
| Calcium Carbonate | 5 | View Report |
| Calcium Chloride | 5 | View Report |
| Capecitabine | 5 | View Report |
| Carbamazepine | 5 | View Report |
| Carbidopa | 5 | View Report |
| Ceftazidime | 5 | View Report |
| Celecoxib | 5 | View Report |
| Cephalexin | 5 | View Report |
| Chloramphenicol | 5 | View Report |
| Cimetidine | 5 | View Report |
| Ciprofloxacin | 5 | View Report |
| Clarithromycin | 5 | View Report |
| Clavulanic Acid | 5 | View Report |
| Clobetasol Propionate | 5 | View Report |
| Clotrimazole | 5 | View Report |
| Cyanocobalamin | 5 | View Report |
| Decitabine | 5 | View Report |
| Deferasirox | 5 | View Report |
| Desloratadine | 5 | View Report |
| Dexamethasone | 5 | View Report |
| Docetaxel | 5 | View Report |
| Entacapone | 5 | View Report |
| Erythromycin | 5 | View Report |
| Ethinylestradiol | 5 | View Report |
| Everolimus | 5 | View Report |
| Ezetimibe | 5 | View Report |
| Famotidine | 5 | View Report |
| Fenofibrate | 5 | View Report |
| Ferrous Fumarate | 5 | View Report |
| Fluconazole | 5 | View Report |
| Fluticasone Propionate | 5 | View Report |
| Folic Acid | 5 | View Report |
| Gliclazide | 5 | View Report |
| Hydrochlorothiazide | 5 | View Report |
| Hydrocortisone | 5 | View Report |
| Hydrocortisone Acetate | 5 | View Report |
| Ibuprofen | 5 | View Report |
| Insulin Glargine | 5 | View Report |
| Insulin Human | 5 | View Report |
| Irbesartan | 5 | View Report |
| Iron | 5 | View Report |
| Ketoconazole | 5 | View Report |
| Lamivudine | 5 | View Report |
| Lamotrigine | 5 | View Report |
| Lenalidomide | 5 | View Report |
| Levodopa | 5 | View Report |
| Lidocaine | 5 | View Report |
| Loratadine | 5 | View Report |
| Magnesium Hydroxide | 5 | View Report |
| Magnesium Trisilicate | 5 | View Report |
| Medroxyprogesterone Acetate | 5 | View Report |
| Meloxicam | 5 | View Report |
| Methotrexate | 5 | View Report |
| Methylprednisolone | 5 | View Report |
| Metronidazole | 5 | View Report |
| Mometasone Furoate | 5 | View Report |
| Naproxen | 5 | View Report |
| Olanzapine | 5 | View Report |
| Omeprazole | 5 | View Report |
| Paclitaxel | 5 | View Report |
| Potassium Chloride | 5 | View Report |
| Prednisolone | 5 | View Report |
| Pregabalin | 5 | View Report |
| Progesterone | 5 | View Report |
| Risperidone | 5 | View Report |
| Rituximab | 5 | View Report |
| Salicylic Acid | 5 | View Report |
| Simvastatin | 5 | View Report |
| Sodium Citrate | 5 | View Report |
| Tadalafil | 5 | View Report |
| Telmisartan | 5 | View Report |
| Testosterone | 5 | View Report |
| Theophylline | 5 | View Report |
| Thiotepa | 5 | View Report |
| Tobramycin | 5 | View Report |
| Tolnaftate | 5 | View Report |
| Triamcinolone | 5 | View Report |
| Trimethoprim | 5 | View Report |
| Valsartan | 5 | View Report |
| Zinc Oxide | 5 | View Report |
L2 Level (2 drugs)
| Drug Name | Predictions | Link |
|---|---|---|
| Glycine | 5 | View Report |
| Norfloxacin | 5 | View Report |
How Evidence Levels Are Determined
Evidence levels are assigned based on the quality and quantity of clinical evidence:
- Clinical Trials: Phase 3 RCTs carry the highest weight
- Systematic Reviews: Meta-analyses of multiple studies
- Study Design: Randomized controlled trials > observational studies
- Sample Size: Larger studies provide stronger evidence
Disclaimer
Drug repurposing predictions are for research purposes only. These predictions have not been clinically validated and should not be used for medical decisions. Always consult healthcare professionals.
Drug repurposing predictions are for research purposes only. These predictions have not been clinically validated and should not be used for medical decisions. Always consult healthcare professionals.